5 ht2a antagonist 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10498	5-HT2A antagonist 1		5-HT Receptor
	5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.		5-HT Receptor
T15414	GR 113808	GR-113808	5-HT Receptor
	GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release.		5-HT Receptor
T4978	Sarpogrelate hydrochloride	MCI-9042	5-HT Receptor
	Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ...		5-HT Receptor
T22921	LE 300		Dopamine Receptor , 5-HT Receptor
	dopamine D1 receptor antagonist		Dopamine Receptor , 5-HT Receptor
T61207	5-HT6/5-HT2A receptor ligand-1
	5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual antagonist for the 5-HT6 and 5-HT2A receptors. It exhibits a K i value of 2 nM and 11 nM for the respective receptors. This compound holds promise for research in ne...
T61837	5-HT6/5-HT2AR antagonist-1
	5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective recep...
T61220	5-HT6/5-HT2A receptor ligand-2
	Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properti...
T11295	Flibanserin-d4	BIMT-17BS D4,BIMT-17 D4,Flibanserin D4	Others
	Flibanserin, a compound identified as BIMT-17, acts as a complete agonist at the serotonin 5-HT1A receptor, with a binding affinity (Ki) of 1 nM, while functioning as an antagonist at the 5-HT2A receptor with a 49 nM aff...		Others
T22044	BGC 20-761
	BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor K i values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761 is a tryptamine analog with a high affinity for 5-HT(6) receptors, that c...
T74668	Zicronapine fumarate
	Zicronapine (Lu 31-130) fumarate, an antipsychotic medication, exhibits potent pro-cognitive effects in animal models and holds promise for treating various neurological and psychiatric conditions. It acts as a strong an...
T37114	SB 242084 dihydrochloride
	SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonistin vitro: SB 242...
T62324	Flibanserin hydrochloride
	Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active 5-HT1A receptor agonist (Ki: 1 nM) and 5-HT2A (Ki: 49 nM) receptor antagonist of 5-hydroxytryptamine. Flibanserin hydrochloride has antidepressant and an...
T63115	Perphenazine dihydrochloride
	Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), 5-HT2A (Ki: 0.6 nM). Perphenazine dihydrochloride is also able to bi...
T60576	Cyproheptadine
	Cyproheptadine is a potent and orally active antagonist of the 5-HT 2A receptor. Cyproheptadine has antidepressant and antiserotonergic effects. Cyproheptadine also has antiplatelet and thromboprotective activities that ...